Microfluidic Electric Impedance Spectroscopy for Malaria Diagnosis

نویسندگان

  • Sungjae Ha
  • Monica Diez-Silva
  • E Du
  • Sung Jae Kim
  • Jongyoon Han
  • Ming Dao
  • Anantha P. Chandrakasan
چکیده

This paper presents a label-free and noninvasive cell-counting assay system for electrical diagnostic tests of Falciparum malaria using electric impedance spectroscopy (EIS). Our system enabled a high-throughput test in a compact form-factor by the integration of a microfluidic device and a custom circuit board. Based on the differentiation of dielectric properties between cells and container medium, the target cells were individually detected by surface charge density and disease state. [1] This method suggests a potential electrical diagnostic test for malaria in portable electronics.

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تاریخ انتشار 2012